"Come on, someone kit me out."
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"High above Horzine's infamous Biotics Laboratory stands the corporate face of the twisted organization. Local police forces were penned in and wholesale slaughtered when they converged on the entrance. The Horzine offices were undergoing a renovation at the time of the outbreak. Because of this, large portions of the building are closed off."
- Avoid camping on the staircases, the AI will eventually grow a brain and spawn enough specimens to trap you and your squad there. [EDIT: This tactic can work with a dedicated team. One person defending each end, with a Field medic running back and forth between between them would suffice. Ideally a Berserker, a Support specialist or a Commando would be preferred for each door, but Sharpshooter's or Firebug's will suffice. Demo's arent really suitable for defending on the frontline, but can fire grenades over the heads of the players on the frontline.]
- There is a trick on the doors that all lead to the staircase. The trick is, you back into the corner on the side of the door that swings open towards. When a Specimen (Or player) opens that door onto you, you will be closed in the corner until It is re-opened. Specimens have no AI for closing doors, so if your friends are on the roof and you have just spawned, this is a good tactic to use if you don't have enough fire power to reach the roof.
- If you are on the second floor by the trader, you can jump out of the window and onto the car bellow to escape from specimens if you are about to be overrun. This costs you about 60-70 health, but possibly more if you miss the car and land on the floor.
A very skilled Field Medic of level 4, 5 or 6 can solo the Patriarch by using a run and gun tactic due to their movement speed bonus, going up and down the stairs closing doors behind them and knowing when it is safe to attack the patriarch.