“The Siren is a real screamer. Very nasty. Her screams actually hurt - and they'll destroy grenades and rockets in mid-air!” —Loading screen tip
The Siren is one of the few specimens with a ranged attack, the others being the Husk, the Patriarch, and to a small extent the Bloat. Its scream, which gives off a visible red disturbance field, is particularly dangerous; it causes large area of effect amounts of damage, is unaffected by a player's armour, destroys explosives, and causes disorientation, similar to recoil, albeit in all directions, that can make killing her at short range troublesome and even dangerous, as the closer the player, the more disoriented they become. The earliest wave on which it can be found in a long game is the third.
The Siren has a tendency to hide behind other specimens as it approaches, which can sometimes make it hard to spot before they get in range. When it is spotted, it should be treated as a priority target and taken out as soon as possible, a task which can often fall to a Sharpshooter to do.
When not screaming, a Siren can be heard complaining with a benign voice.
The Siren is one of only four females on the game, the others being the Stalker, the Trader and Ash Harding It appears as a short, malnourished individual wearing only a series of thick leather straps, which are primarily used to bind its arms to their body. As a result, most of the Siren's skin can be seen; dark veins cover most of her body, Its eyes are missing and the areas around them are bloodied; however, due to another of Horzine's experiments, she is able to sense nearby humans without the need for sight. Their mouths are nearly always open, with their teeth visibly on show, either to intimidate, or due to certain facial muscles being too weak to close it. Because her arms are tied down, her secondary attack is to bite when in extremely close proximity to humans.
For the Twisted Christmas update, she was reskinned as a caroler wearing a green dress, tied up in Christmas lights. For the Summer Sideshow update, she was re-skinned as a "The Bearded Beauty"; an average-sized female humanoid wearing a green summer dress, however, her arms are stubs, ending with malformed fingers. As her name suggests, she also has a very thick and scraggly black beard and thick eyebrows, and is also wearing a pink headband. For the Halloween Event she was based on her Summer skin, but renamed the "Scream Fucker". She donned a pirate hat and has hooks instead of stubs
The Siren has similar behavior patterns to the Clot. It walks at a slow pace towards the players, and when within range, screams. It can be generally found amongst a large crowd hiding her tiny frame behind other large specimen such as Scrake, Bloat or Fleshpound. At that state she keeps her head straight and attempts to talk to other specimen, her benign voice can be heard saying "Can you see?". When players are at its range it nods her head first, slows down her pace then raises her head and leashes out an ear shattering scream. The Siren's scream can exterminate and neutralize any explosives within its effective radius, including the Husk fireball launcher's fireball and Field Medic rifle morphine darts. If a player manages to get close enough to one before it starts preparing to scream, it may attempt to bite the player, which can actually do quite a bit of damage, but unlike their scream, it does not cause any other detrimental effects and only damages the bitten player.
 Historic data
One of the biggest gameplay differences involving the Siren in the mod has to do with her scream; it didn't let off a visible disturbance field as it does now, meaning that unprepared players could often fail to locate and dispatch her before suffering serious losses. Her physical appearance was quite similar however, despite some quite different features; her hair was relatively tidy, about shoulder length with a red tinge. She also wore a straitjacket instead of a system of straps.
The Siren is a clone of Clamely's wife, who had long wanted to be a singer but lacked in talent. Their eyes were gouged out so that they could not see (thus, know when to scream), and they were all restrained with straight jackets. Kevin Clamely had a Siren kill his wife when she attempted to divorce him.
The Siren does not have a particularly large amount of health; at most 20% more than the Gorefast; however, its head is 8–10 times more durable than the Gorefasts', making the Siren harder to kill via a headshot with less powerful weapons. Weapons such as the lever-action rifle or M14 EBR are particularly effective at ranged decapitation, and other weapons with long effective ranges are also useful for eliminating her.
The Siren's scream cannot inflict damage through doors and walls, however, the red field passes through all objects; this allows players to wait behind doors for her to come through, therefore a player, such as a Berserker, can safely dispatch her at short range with the appropriate cover.
The Siren's scream can neutralize any explosives, such as pipe bombs, grenades, and L.A.W rockets, within its effective radius by disintegrating them into red particles. Amusingly, this also applies to the Husk's fireballs, which can lead to a Siren "saving" you from a Husk if timed correctly. Explosives are effective against the Siren if they are detonated before it is close enough to scream, despite generally not being the most cost-effective means for dealing with it.
 Wave distribution
The Siren starts making her appearance early in the game; wave two for a short game, and wave three for medium and long.
 Total health
The base hit points of the Siren is 300; its total health on normal with one player, and for every additional player 30 hit points is added. This figure is then multiplied by 0.5 on beginner, 1 on normal, 1.35 on hard, 1.55 for suicidal, and 1.75 for hell on earth.
|Players||Beginner||Normal||Hard||Suicidal||Hell on Earth|
 Head health
The base hit points of the Siren's head is 200; its total health on normal with one player, and for every additional player 10 hit points is added. This figure is then multiplied by 0.5 on beginner, 1 on normal, 1.35 on hard, 1.55 for suicidal, and 1.75 for hell on earth.
|Players||Beginner||Normal||Hard||Suicidal||Hell on Earth|
|Beginner||Normal||Hard||Suicidal||Hell on Earth|
- The Siren is based off the mythological creature, the Siren, in which it lured sailors with their their enchanting singing to shipwreck them.
- The Siren had a Left 4 Dead counterpart, 'The Screamer.'
- There is a Siren in the game Dead Frontier, as a girl with a red dress and two heads.
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